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Recombinant Human CD93 Protein, C-hFc and His tag

Recombinant Human CD93 Protein, C-hFc and His tag

产品编号

KMH266

别名

CD93分子, C1QR1, C1qRP, CDw93, ECSM3, MXRA4, C1qR(P), dJ737E23.1, CD93 molecule

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberKMH266
AliasCD93分子, C1QR1, C1qRP, CDw93, ECSM3, MXRA4, C1qR(P), dJ737E23.1, CD93 molecule
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionKMH266 Recombinant Human CD93 Protein, C-hFc and His tag contains the human CD93(24-580 aa) was expressed in Mammalian cells.
Molecular NameCD93
Product IntroductionCD93参与调节免疫反应,促进炎症反应中的免疫细胞活化。
Molecular Weight100-130 kDa
Expression SystemHEK293F Cells
SpeciesHuman
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
PurificationAffinity Purification
Uniprot IDQ9NPY3
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationPBS
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundCD93, also known as Complement component C1q receptor, is receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). This protein mediates the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. It may play a role in intercellular adhesion. This protein was expressed on (pre)plasmablasts/plasma cells, including long-lived plasma cells that showed decreased cell cycle activity, high levels of isotype-switched Ig secretion, and modification of the transcriptional network. It is important for the maintenance of plasma cells in bone marrow niches.
Endotoxin< 0.1 EU per ug
Protein FamilyCD molecule
Biological ActivityMeasured by its ability to induce TNF-alpha secretion by THP‑1 human acute monocytic leukemia cells. The ED50 forthis effect is 6-30 μg/mL.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。
FAQ
  • 如何评估已表达蛋白的活性?

    可以通过特定的酶活性实验、受体结合实验或细胞实验来评估蛋白的生物活性。

  • 已表达蛋白的溶解性如何提高?

    可以通过优化表达条件、使用适当的去污剂或分子伴侣蛋白来提高蛋白的溶解性。

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