Recombinant Human CD93 Protein, C-hFc and His tag
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产品编号
KMH266
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别名
CD93分子, C1QR1, C1qRP, CDw93, ECSM3, MXRA4, C1qR(P), dJ737E23.1, CD93 molecule
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
| Catalog Number | KMH266 |
| Alias | CD93分子, C1QR1, C1qRP, CDw93, ECSM3, MXRA4, C1qR(P), dJ737E23.1, CD93 molecule |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH266 Recombinant Human CD93 Protein, C-hFc and His tag contains the human CD93(24-580 aa) was expressed in Mammalian cells. |
| Molecular Name | CD93 |
| Product Introduction | CD93参与调节免疫反应,促进炎症反应中的免疫细胞活化。 |
| Molecular Weight | 100-130 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| Purification | Affinity Purification |
| Uniprot ID | Q9NPY3 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | CD93, also known as Complement component C1q receptor, is receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). This protein mediates the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. It may play a role in intercellular adhesion. This protein was expressed on (pre)plasmablasts/plasma cells, including long-lived plasma cells that showed decreased cell cycle activity, high levels of isotype-switched Ig secretion, and modification of the transcriptional network. It is important for the maintenance of plasma cells in bone marrow niches. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | CD molecule |
| Biological Activity | Measured by its ability to induce TNF-alpha secretion by THP‑1 human acute monocytic leukemia cells. The ED50 forthis effect is 6-30 μg/mL. |
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |
可以通过特定的酶活性实验、受体结合实验或细胞实验来评估蛋白的生物活性。
可以通过优化表达条件、使用适当的去污剂或分子伴侣蛋白来提高蛋白的溶解性。
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