Recombinant Human CD86 Protein, C-His tag
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产品编号
KMH261
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别名
CD86分子, B70, B7 2, B7.2, LAB72, CD28LG2, CD86 molecule [ Homo sapiens
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Catalog Number | KMH261 |
| Alias | CD86分子, B70, B7 2, B7.2, LAB72, CD28LG2, CD86 molecule [ Homo sapiens |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH261 Recombinant Human CD86 Protein, C-His tag contains the human CD86(26-247 aa) was expressed in Mammalian cells. |
| Molecular Name | CD86 |
| Product Introduction | (KMH261) CD86是T细胞激活的共刺激分子，在免疫应答中发挥重要作用。 |
| Molecular Weight | 57-66 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | P42081 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS, pH7.5 |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | B7-1 and B7-2, together with their receptors CD28 and CTLA-4, constitute one of the dominant costimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 2 - 1 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | CD molecule |
| Biological Activity | Immobilized Recombinant Human CD86 at 2 μg/mL (100 μL/well) can bind Recombinant Human CTLA-4 with a linearrange of 10-40 ng/mL. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
FAQ
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已表达的蛋白能否用于疫苗开发？
是的，重组蛋白可以用于疫苗的开发，特别是在生产抗原性蛋白和研究免疫反应方面。
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