Recombinant Human CD84 Protein, C-His tag
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产品编号
KMH249
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别名
CD84分子, LY9B, hCD84, mCD84, SLAMF5, CD84 molecule
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Catalog Number | KMH249 |
| Alias | CD84分子, LY9B, hCD84, mCD84, SLAMF5, CD84 molecule |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH249 Recombinant Human CD84 Protein, C-His tag contains the human CD84(35-43 kDa) was expressed in Mammalian cells. |
| Molecular Name | CD84 |
| Product Introduction | CD84是免疫细胞表面的分子，参与免疫细胞的激活和细胞间的信号传递。 |
| Molecular Weight | 35-43 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | Q9UIB8 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Human CD83 is a 4-5 kDa member of the Siglec (or sialic-acid-binding immunoglobulin-like lectin) family of transmembrane proteins. CD83 is a primary marker for dendritic cells. It is also found on B cells, neutrophils, monocytes and macrophages. Except for dendritic cells, CD83 expression is often transient. CD83 binds to sialic acids on target cells. Membrane CD83 promotes T cell proliferation, particularly of CD8+ cytotoxic T cells. Soluble CD83 is immunosuppressive and blocks T cell activation. On monocytes, CD83 is suggested to drive monocytes into a fibrocyte phenotype. A lack of membrane-expressed CD83 leads to an unusual IL-4/ IL-1 producing CD4+ T cell phenotype. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | CD molecule |
| Biological Activity | Measured in a cell proliferation assay using PHA stimulated human T cells in the presence of antiCD3. The ED50 forthis effect is 1- 4 μg/mL in the presence of antiCD3 immobilized at least at 20 ng/mL. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
FAQ
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如何评估已表达蛋白的活性？
可以通过特定的酶活性实验、受体结合实验或细胞实验来评估蛋白的生物活性。
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已表达蛋白的溶解性如何提高？
可以通过优化表达条件、使用适当的去污剂或分子伴侣蛋白来提高蛋白的溶解性。
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