Recombinant Human CD83 Protein, C-His tag_天津卡梅德科技发展有限公司

Recombinant Human CD83 Protein, C-His tag

产品编号

KMH248

别名

CD83分子, BL11, HB15, CD83 molecule

规格

20ug
50ug
100ug
200ug
1mg

DATASHEET MSDS

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产品介绍

Catalog Number	KMH248
Alias	CD83分子, BL11, HB15, CD83 molecule
Size	20ug, 50ug, 100ug, 200ug, 1mg
Product Description	KMH248 Recombinant Human CD83 Protein, C-His tag contains the human CD83(Thr20-Ala143) was expressed in Mammalian cells.
Molecular Name	CD83
Product Introduction	(KMH248) CD83参与调节免疫反应，尤其在树突状细胞的成熟和功能中起作用。
Molecular Weight	18-25 kDa
Expression System	HEK293F Cells
Species	Human
Concentration	联系销售经理获得最新批次的浓度
Purity	≥90%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	Q01151
Storage Condition	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation	PBS, pH7.5
Shipping Condition	This product is shipped on ice packs or dry ice.
Background	Human CD83 is a 4-5 kDa member of the Siglec (or sialic-acid-binding immunoglobulin-like lectin) family of transmembrane proteins. CD83 is a primary marker for dendritic cells. It is also found on B cells, neutrophils, monocytes and macrophages. Except for dendritic cells, CD83 expression is often transient. CD83 binds to sialic acids on target cells. Membrane CD83 promotes T cell proliferation, particularly of CD8+ cytotoxic T cells. Soluble CD83 is immunosuppressive and blocks T cell activation. On monocytes, CD83 is suggested to drive monocytes into a fibrocyte phenotype. A lack of membrane-expressed CD83 leads to an unusual IL-4/ IL-1 producing CD4+ T cell phenotype.
Endotoxin	< 0.1 EU per ug
Protein Family	CD molecule
Biological Activity	Measured by the ability of the immobilized protein to support the adhesion of human monocytederived dendritic cells. When 5 x 104 cells/well are added to human CD83/Fc Chimera coated plates (5 µg/mL, 100 µL/well), approximately 50- 75% will adhere after 3
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。