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Recombinant Human CD31 Protein, C-His tag

Recombinant Human CD31 Protein, C-His tag

产品编号

KMH186

别名

血小板内皮细胞黏附分子1, CD31, PECA1, GPIIA', PECAM 1, endoCAM, CD31/EndoCAM, platelet and endothelial cell adhesion molecule 1

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberKMH186
Alias血小板内皮细胞黏附分子1, CD31, PECA1, GPIIA', PECAM 1, endoCAM, CD31/EndoCAM, platelet and endothelial cell adhesion molecule 1
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionKMH186 Recombinant Human CD31 Protein, C-His tag contains the human PECAM1(Gln28-Lys601) was expressed in Mammalian cells.
Molecular NamePECAM1
Product IntroductionPECAM1 (KMH186) 在白血球穿越血管壁及内皮细胞间的黏附作用中起作用。
Molecular Weight85-105 kDa
Expression SystemHEK293F Cells
SpeciesHuman
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
SDS-PAGE
PurificationAffinity Purification
Uniprot IDP16284
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationPBS
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundThe CD31 adhesion molecule, also known as PECAM-1, is expressed in large amounts on endothelial cells at intercellular junctions and on T-cell subsets, and to a lesser extent on platelets and most other leukocytes such as monocytes and neutrophils. CD31 binds to itself homotypically, and also to the leukocyte integrinαvβ3 heterotypically. CD31 is required for the transendothelial migration of leukocytes through intercellular junctions of vascular endothelial cells. CD31 has been found in human plasma, and the presence of this circulating isoform is suggested to modulate the transendothelial migration of leukocytes.A DNA sequence encoding the extracellular domain (Met 1- Lys 61 ) of human CD31 (NP_433.3) precursor was expressed with the fused Fc region of human IgG1 at the C-terminus.
Endotoxin< 0.1 EU per ug
Protein FamilyCD molecule
Biological ActivityMeasured by the ability of the immobilized protein to support the adhesion of Jurkat human acute T cell leukemia cells. When 8×104 cells/well are added to CD31 coated plates (5μg/mL, 100 μL/well) in the presence of 10 μg/mL PHA,approximately 60-70% will a
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。
FAQ
  • 已表达蛋白可以长期保存吗?

    如果储存条件合适(例如-80°C冷冻),蛋白可以长期保存,通常推荐储存时间不超过一年。

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