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Recombinant Human SPARC Protein, His Tag

Recombinant Human SPARC Protein, His Tag

产品编号

KMH1741

别名

ON, ONT, OI17, BM 40, secreted protein acidic and cysteine rich

规格
  • 50ug
  • 100ug
产品介绍
AliasON, ONT, OI17, BM 40, secreted protein acidic and cysteine rich
Catalog NumberKMH1741
Molecular NameSPARC
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundSPARC, an acronym for secreted protein, acidic and rich in cysteine, is also known as osteonectin or BM-4. It is the founding member of a family of secreted matricellular proteins with similar domain structure. The 33 amino acid, 43 kDa protein contains a 17 aa signal sequence, an N-terminal acidic region that binds calcium, a follistatin domain containing Kazal-like sequences, and a C-terminal extracellular calcium (EC) binding domain with two EF-hand motifs. SPARC is produced by fibroblasts, capillary endothelial cells, platelets and macrophages, especially in areas of tissue morphogenesis and remodeling. SPARC shows context-specific effects, but generally inhibits adhesion, spreading and proliferation, and promotes collagen matrix formation.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight31.46 kDa
Note仅供科研使用

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