Recombinant Human Semaphorin 3A/SEMA3A Protein, His Tag_天津卡梅德科技发展有限公司

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Recombinant Human Semaphorin 3A/SEMA3A Protein, His Tag

Recombinant Human Semaphorin 3A/SEMA3A Protein, His Tag

产品编号

KMH1675

别名

HH16, SemD, COLL1, SEMA1, SEMAD, SEMAL, coll 1, Hsema I, SEMAIII, Hsema III, semaphorin 3A

规格

50ug
100ug

DATASHEET MSDS

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产品介绍

Alias	HH16, SemD, COLL1, SEMA1, SEMAD, SEMAL, coll 1, Hsema I, SEMAIII, Hsema III, semaphorin 3A
Catalog Number	KMH1675
Molecular Name	SEMA3A
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	Other protein
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	Semaphorins are a family of secreted and cell-bound signaling molecules defined by the presence of a common 5 aa Sema domain. They are best characterized in relation to axon guidance during development of the nervous system. The functions of Semaphorins 3A (SEMA3A) are mediated primarily through binding to the Neuropilin-1 (Npn-1) and Plexin-A1 coreceptor complex. Neuropilins lack a signaling-competent cytoplasetmic domain and ensure semaphorin binding, whereas the transmembrane receptor plexin mediates the intracellular response. As the first identified vertebrate semaphorin, SEMA3A functions either as a chemorepulsive agent inhibiting axonal outgrowth, or as a chemoattractive agent stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Its overexpression is associated with schizophrenia which is seen in various human tumor cell lines, and aberrant release is associated with the progression of Alzheimer"s disease.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	82.61 kDa
Note	仅供科研使用

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