重组人R-脊椎蛋白1, His标签|Recombinant Human RSPO1 Protein, His Tag
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产品编号
KMH1655
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别名
R-促进因子1,R-脊椎蛋白1,RSPO1,R-spondin 1,RSPO,CRISTIN3
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
| Catalog Number | KMH1655 |
| Alias | R-促进因子1,R-脊椎蛋白1,RSPO1,R-spondin 1,RSPO,CRISTIN3 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Molecular Name | RSPO1 |
| Product Introduction | R-脊椎蛋白1是一种分泌蛋白,通过特异性增强Wnt/β-catenin信号通路的活性,从而促进细胞的增殖与分化。 |
| Molecular Weight | 25.63 kDa |
| Expression System | Mammalian cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥90% as determined by SDS-PAGE |
| Purification | Affinity Purification |
| Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | R-Spondin-1 (Rspo-1) belongs to the (Rspo) family of Wnt modulators. Currently, the family consists of four structurally related secreted ligands (Rspo 1-4), all containing the furin-like and thrombospondin structural domains. Rspo-1 is expressed in certain areas of the developing central nervous system, as well as in the adrenal glands, ovary, testis, thyroid, and trachea. Rspo can interact with the Frizzled/LRP6 receptor complex in a manner that stimulates the Wnt/beta-catenin signaling pathway. |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Protein Family | Other protein |
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |
可在纯化过程中加入蛋白酶抑制剂、低温操作,优化储存条件(如分装冻存于-80°C),并避免反复冻融。某些情况下,可选用蛋白酶缺陷型宿主菌减少降解风险。
常用SDS-PAGE、Western Blot检测表达,BCA/Bradford法测浓度,HPLC或质谱分析纯度,生物活性实验(如ELISA、酶活检测)验证功能。
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