Recombinant Human P4HB Protein, C-10*His tag
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产品编号
KMH1499
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别名
蛋白二硫键异构酶, DSI, GIT, PDI, PHDB, PDIA1, PO4DB, PO4HB, PROHB, CLCRP1, ERBA2L, P4Hbeta, prolyl 4 hydroxylase subunit beta
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Catalog Number | KMH1499 |
| Alias | 蛋白二硫键异构酶, DSI, GIT, PDI, PHDB, PDIA1, PO4DB, PO4HB, PROHB, CLCRP1, ERBA2L, P4Hbeta, prolyl 4 hydroxylase subunit beta |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH1499 Recombinant Human P4HB Protein, C-10*His tag contains the human P4HB(18-505 aa) was expressed in Mammalian Cells. |
| Molecular Name | P4HB |
| Product Introduction | P4HB (KMH1499) 参与蛋白质折叠和修饰，尤其是参与二硫键的形成与解离。 |
| Molecular Weight | 60 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥90% |
| SDS-PAGE | |
| Purification | Affinity Purification |
| Uniprot ID | P07237 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | Other protein |
| Biological Activity | Measured by its ability to promote aggregation of insulin in the presence of DTT. The specific activity is >7.5 A650/cm/min/mg, as measured underthe described conditions. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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