Recombinant Human MICA Protein, C-His tag_天津卡梅德科技发展有限公司

Recombinant Human MICA Protein, C-His tag

产品编号

KMH1401

别名

MICAMIC A, PERB11.1, MICA MHC class I polypeptide related sequence A

规格

20ug
50ug
100ug
200ug
1mg

DATASHEET MSDS

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产品介绍

Catalog Number	KMH1401
Alias	MICAMIC A, PERB11.1, MICA MHC class I polypeptide related sequence A
Size	20ug, 50ug, 100ug, 200ug, 1mg
Product Description	KMH1401 Recombinant Human MICA Protein, C-His tag contains the human MICA(1-308 aa) was expressed in Mammalian cells.
Molecular Name	MICA
Product Introduction	(KMH1401) MICA是免疫监视分子，作为自然杀伤细胞的激活因子参与免疫应答。
Molecular Weight	55-65 kDa
Expression System	HEK293F Cells
Species	Human
Concentration	联系销售经理获得最新批次的浓度
Purity	≥95%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	Q29983
Storage Condition	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation	PBS
Shipping Condition	This product is shipped on ice packs or dry ice.
Background	MIC-A (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig-like domains, but they have no capacity to bind peptide or interact with 2-microglobulin. The genes encoding these proteins are found within the Major Histocompatibility Complex on human chromosome 6. The MICA locus is highly polymorphic with more than 5 recognized human alleles. MICA is absent from most cells but is frequently expressed in epithelial tumors and can be induced by bacterial and viral infections.
Endotoxin	< 0.1 EU per ug
Protein Family	Other protein
Biological Activity	Immobilized Recombinant Human MICA Protein at 2 μg/mL (100 μL/well) can bind NKG2D with a linearrange of 0.61-14.3 ng/mL.
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。