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Recombinant Human MANF Protein, No tag

Recombinant Human MANF Protein, No tag

产品编号

KMH1374

别名

MANF蛋白, ARP, ARMET, mesencephalic astrocyte derived neurotrophic factor

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberKMH1374
AliasMANF蛋白, ARP, ARMET, mesencephalic astrocyte derived neurotrophic factor
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionKMH1374 Recombinant Human MANF Protein, No tag contains the human MANF(25-182 aa) was expressed in E. coli.
Molecular NameMANF
Product Introduction (KMH1374) MANF参与保护细胞免受应激损伤,促进细胞生存。
Molecular Weight18 kDa
Expression SystemE. coli
SpeciesHuman
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
PurificationAffinity Purification
Uniprot IDP55145
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationPBS
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundMANF is a neurotrophic factor found mainly in central nervous tissues where it may remain localized to the endoplasmic reticulum/Golgi apparatus, or secreted. It has been shown that MANF plays an important role in protecting cells against tunicamycin and thapsigargin -induced cell death. Without MANF, cells become increasingly vulnerable to the aforementioned drugs. Also, MANF is structurally homologous to CDNF.
Endotoxin< 0.1 EU per ug
Protein FamilyOther protein
Biological ActivityMeasured by its ability to support the survival and stimulate neurite outgrowth ofrat embryonic cortical neurons. The ED50 forthis effect is 0.7-2.8 μg/mL.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。

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