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Recombinant Human MAN1B1 Protein, His Tag

Recombinant Human MAN1B1 Protein, His Tag

产品编号

KMH1373

别名

MRT15, ERMAN1, ERManI, MANA ER, mannosidase alpha class 1B member 1

规格
  • 50ug
  • 100ug
产品介绍
AliasMRT15, ERMAN1, ERManI, MANA ER, mannosidase alpha class 1B member 1
Catalog NumberKMH1373
Molecular NameMAN1B1
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundEndoplasmic Reticulum Mannosyl-Oligosaccharide 1, 2-α-Mannosidase (MAN1B1) belongs to the glycosyl hydrolase 47 family. MAB1B1 is a single-pass type II membrane protein and widely expressed in many tissues. MAB1B1 is involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. MAB1B1 can be inhibited by both 1-deoxymannojirimycin (dMNJ) and kifunensine. Defects in MAN1B1 are the cause of mental retardation autosomal recessive type 15 (MRT15). Mental retardation is characterized by significantly below average general intellectual functioning, it is also associated with impairments in adaptative behavior and manifested during the developmental period.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight65.34 kDa
Note仅供科研使用

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