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Recombinant Human LYVE-1 Protein, His Tag

Recombinant Human LYVE-1 Protein, His Tag

产品编号

KMH1369

别名

HAR, XLKD1, LYVE 1, CRSBP 1, lymphatic vessel endothelial hyaluronan receptor 1

规格
  • 50ug
  • 100ug
产品介绍
AliasHAR, XLKD1, LYVE 1, CRSBP 1, lymphatic vessel endothelial hyaluronan receptor 1
Catalog NumberKMH1369
Molecular NameLYVE-1
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundLYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight24.09 kDa
Note仅供科研使用

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