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Recombinant Human LYVE-1 Protein, C-His tag

Recombinant Human LYVE-1 Protein, C-His tag

产品编号

KMH1369

别名

LYVE-1, HAR, XLKD1, LYVE 1, CRSBP 1, lymphatic vessel endothelial hyaluronan receptor 1

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberKMH1369
AliasLYVE-1, HAR, XLKD1, LYVE 1, CRSBP 1, lymphatic vessel endothelial hyaluronan receptor 1
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionKMH1369 Recombinant Human LYVE-1 Protein, C-His tag contains the human LYVE1(24-238 aa) was expressed in Mammalian cells.
Molecular NameLYVE-1
Product IntroductionLYVE-1参与淋巴细胞的迁移与内皮细胞的交互。
Molecular Weight40-60 kDa
Expression SystemHEK293F Cells
SpeciesHuman
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
PurificationAffinity Purification
Uniprot IDQ9Y5Y7
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationPBS
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundLYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
Endotoxin< 0.1 EU per ug
Protein FamilyOther protein
Biological ActivityMeasured by its ability to bind hyaluronan in a functional ELISA.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。

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