Recombinant Human LCP2 Protein, His Tag_天津卡梅德科技发展有限公司

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Recombinant Human LCP2 Protein, His Tag

Recombinant Human LCP2 Protein, His Tag

产品编号

KMH1330

别名

SLP76, SLP 76, lymphocyte cytosolic protein 2

规格

50ug
100ug

DATASHEET MSDS

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产品介绍

Alias	SLP76, SLP 76, lymphocyte cytosolic protein 2
Catalog Number	KMH1330
Molecular Name	LCP2
Species	Human
Host	E. coli
Size	50ug, 100ug
Protein Family	Other protein
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	Please contact our customer service for more information.
Formulation	PBS
Background	SLP-76 was originally identified as a substrate of the ZAP-7 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain. A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein. Studies using SLP-76 deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	58.63 kDa
Note	仅供科研使用

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