Recombinant Human IL17/IL17A Protein, C-His tag
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产品编号
KMH129
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别名
IL17A细胞因子, IL17, CTLA8, IL 17, CTLA 8, IL 17A, interleukin 17A
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Catalog Number | KMH129 |
| Alias | IL17A细胞因子, IL17, CTLA8, IL 17, CTLA 8, IL 17A, interleukin 17A |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH129 Recombinant Human IL17/IL17A Protein, C-His tag contains the human IL17A(Gly24-Ala155) was expressed in Mammalian cells. |
| Molecular Name | IL17A |
| Product Introduction | IL17A在免疫反应中调节炎症反应，特别在慢性炎症中起重要作用。 |
| Molecular Weight | 18-25 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥90% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | Q16552 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | IL17 is a proinflammatory cytokine produced by activated T cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. Interleukin-17 can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | Interleukin |
| Biological Activity | Measured by its ability to induce IL-6 secretion by Hela cells. The ED50 for this effect is 2.64-10.58 ng/mL, corresponding to a specific activity of 9.45×104~3.79×105 units/mg. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
FAQ
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表达后的蛋白是否需要去除标签？
如果使用了亲和标签（如His标签、GST标签），并且标签对实验结果有影响，可以通过酶切去除标签。
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