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Recombinant Human IGFBP-5/IGFBP5 Protein, C-His tag

Recombinant Human IGFBP-5/IGFBP5 Protein, C-His tag

产品编号

KMH1260

别名

胰岛素样生长因子结合蛋白5, IBP5, insulin like growth factor binding protein 5

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberKMH1260
Alias胰岛素样生长因子结合蛋白5, IBP5, insulin like growth factor binding protein 5
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionKMH1260 Recombinant Human IGFBP-5/IGFBP5 Protein, C-His tag contains the human IGFBP5(21-272 aa) was expressed in Mammalian cells.
Molecular NameIGFBP5
Product IntroductionIGFBP5 (KMH1260) 通过与胰岛素样生长因子结合,调节细胞生长和代谢。
Molecular Weight35-37 kDa
Expression SystemHEK293F Cells
SpeciesHuman
Concentration联系销售经理获得最新批次的浓度
Purity≥90%
SDS-PAGE
PurificationAffinity Purification
Uniprot IDP24593
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationPBS
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundMouse Insulin-like Growth Factor Binding Protein-5 (mIGFBP-5) is a 252 amino acid protein that is one of the six "classical" IGF binding proteins that play an important role in stabilizing and regulating the activity of IGFs in vivo. Mouse IGFBP-5 preferentially binds IGF-II and it also binds with high affinity to extracellular matrix components which protect it from proteolysis. Like human IGFBP-5, mouse IGFBP-5 has a nuclear targeting sequence.
Endotoxin< 0.1 EU per ug
Protein FamilyOther protein
Biological ActivityMeasured by its ability to inhibit the biological activity of IGF-I orIGF-II on MCF‑7 human breast cancer cells. The ED50 forthis effect is 0.5‑1.5 µg/mL in the presence of 14 ng/mL rhIGF-II.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。

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