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Recombinant Human IGFBP-4/IGFBP4 Protein, His Tag

Recombinant Human IGFBP-4/IGFBP4 Protein, His Tag

产品编号

KMH1259

别名

BP 4, IBP4, IGFBP 4, HT29 IGFBP, insulin like growth factor binding protein 4

规格
  • 50ug
  • 100ug
产品介绍
AliasBP 4, IBP4, IGFBP 4, HT29 IGFBP, insulin like growth factor binding protein 4
Catalog NumberKMH1259
Molecular NameIGFBP4
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundIGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP4 is the major IGF-BP produced by osteoblasts, and is also found in the epidermis, ovarian follicles, and other tissues. IGF-BP4 inhibits the activity of IGF-I and IGF-II by binding in a manner that results in the formation of complexes with reduced ability to signal through cell surface IGF receptors. IGF-BP4 can inhibit the growth of chick pelvis cartilage and HT29 colon adenocarcinoma cells by blocking the mitogenic actions of IGFs, and has also been shown to reduce colony formation by colorectal cancer cells via an IGF independent pathway.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight26.07 kDa
Note仅供科研使用

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