Recombinant Human IGFBP-4/IGFBP4 Protein, C-His tag_天津卡梅德科技发展有限公司

Recombinant Human IGFBP-4/IGFBP4 Protein, C-His tag

产品编号

KMH1259

别名

胰岛素样生长因子结合蛋白4, BP 4, IBP4, IGFBP 4, HT29 IGFBP, insulin like growth factor binding protein 4

规格

20ug
50ug
100ug
200ug
1mg

DATASHEET MSDS

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产品介绍

Catalog Number	KMH1259
Alias	胰岛素样生长因子结合蛋白4, BP 4, IBP4, IGFBP 4, HT29 IGFBP, insulin like growth factor binding protein 4
Size	20ug, 50ug, 100ug, 200ug, 1mg
Product Description	KMH1259 Recombinant Human IGFBP-4/IGFBP4 Protein, C-His tag contains the human IGFBP4(Met1-Glu258) was expressed in Mammalian cells.
Molecular Name	IGFBP4
Product Introduction	IGFBP4 (KMH1259) 调节胰岛素样生长因子的功能，参与细胞生长调控。
Molecular Weight	35 kDa
Expression System	HEK293F Cells
Species	Human
Concentration	联系销售经理获得最新批次的浓度
Purity	≥95%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	P22692
Storage Condition	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation	PBS
Shipping Condition	This product is shipped on ice packs or dry ice.
Background	IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP4 is the major IGF-BP produced by osteoblasts, and is also found in the epidermis, ovarian follicles, and other tissues. IGF-BP4 inhibits the activity of IGF-I and IGF-II by binding in a manner that results in the formation of complexes with reduced ability to signal through cell surface IGF receptors. IGF-BP4 can inhibit the growth of chick pelvis cartilage and HT29 colon adenocarcinoma cells by blocking the mitogenic actions of IGFs, and has also been shown to reduce colony formation by colorectal cancer cells via an IGF independent pathway.
Endotoxin	< 0.1 EU per ug
Protein Family	Other protein
Biological Activity	Measured by its ability to bind Human IGF1. The ED50 for this effect is 1.95-111.32 ng/mL.
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。