Recombinant Human IGFBP-4/IGFBP4 Protein, His Tag
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产品编号
KMH1259
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别名
BP 4, IBP4, IGFBP 4, HT29 IGFBP, insulin like growth factor binding protein 4
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规格
- 50ug
- 100ug
Alias | BP 4, IBP4, IGFBP 4, HT29 IGFBP, insulin like growth factor binding protein 4 |
Catalog Number | KMH1259 |
Molecular Name | IGFBP4 |
Species | Human |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | Other protein |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | PBS |
Background | IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP4 is the major IGF-BP produced by osteoblasts, and is also found in the epidermis, ovarian follicles, and other tissues. IGF-BP4 inhibits the activity of IGF-I and IGF-II by binding in a manner that results in the formation of complexes with reduced ability to signal through cell surface IGF receptors. IGF-BP4 can inhibit the growth of chick pelvis cartilage and HT29 colon adenocarcinoma cells by blocking the mitogenic actions of IGFs, and has also been shown to reduce colony formation by colorectal cancer cells via an IGF independent pathway. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 26.07 kDa |
Note | 仅供科研使用 |