Recombinant Human IL12B Protein, C-His tag
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产品编号
KMH124
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别名
白细胞介素13B, CLMF, NKSF, CLMF2, IMD28, IMD29, NKSF2, IL 12B, interleukin 13B
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Catalog Number | KMH124 |
| Alias | 白细胞介素13B, CLMF, NKSF, CLMF2, IMD28, IMD29, NKSF2, IL 12B, interleukin 13B |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH124 Recombinant Human IL12B Protein, C-His tag contains the human IL12B(23-328 aa) was expressed in Mammalian cells. |
| Molecular Name | IL13B |
| Product Introduction | (KMH124) IL13B参与调节免疫系统，尤其在过敏性反应和免疫耐受性中起作用。 |
| Molecular Weight | 50 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| Purification | Affinity Purification |
| Uniprot ID | P29460 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS, pH7.5 |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Interleukin 13 (IL-13) is a single-chain cytokine which belongs to the IL13/IL4 family. In humans, IL13 is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL13 inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. Meanwhile, IL-13 synergizes with IL2 in regulating IFN-gamma synthesis. IL-13 binds to a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL13 Rα1 and IL13 Rα2), and exerts its effects through signal transducer and activator of transcription 6 (STAT6), like IL-4. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | Interleukin |
| Biological Activity | Measured by its ability to enhance IFNgamma secretion in NK-92 human natural killer lymphoma cells. The ED50 for this effect is 2.00-20.0 ng/mL. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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