Recombinant Human HMGB1 Protein, No Tag_天津卡梅德科技发展有限公司

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Recombinant Human HMGB1 Protein, No Tag

Recombinant Human HMGB1 Protein, No Tag

产品编号

KMH1216

别名

HMG1, HMG3, HMG 1, SBP 1, high mobility group box 2

规格

50ug
100ug

DATASHEET MSDS

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产品介绍

Alias	HMG1, HMG3, HMG 1, SBP 1, high mobility group box 2
Catalog Number	KMH1216
Molecular Name	HMGB1
Species	Human
Host	E. coli
Size	50ug, 100ug
Protein Family	Other protein
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	Please contact our customer service for more information.
Formulation	PBS
Background	High-mobility group box 1 protein (HMGB1), previously known as HMG-1 or amphoterin, is a member of the high mobility group box family of non-histone chromosomal proteins. Human HMGB1 is expressed as a 3 kDa, 215 amino acid (aa) single chain polypeptide containing three domains: two N-terminal globular, 7 aa positively charged DNA-binding domains (HMG boxes A and B), and a negatively charged 3 aa C-terminal region that contains only Asp and Glu.4, 5 Residues 27 - 43 and 178 - 184 contain a NLS. Posttranslational modifications of the molecule have been reported, with acetylation occurring on as many as 17 lysine residues. HMGB1 is expressed at high levels in almost all cells. It was originally discovered as a nuclear protein that could bend DNA. Such bending stabilizes nucleosome formation and regulates the expression of select genes upon recruitment by DNA binding proteins.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	9.68 kDa
Note	仅供科研使用

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