Recombinant Human GFRA2 C-fc Protein, C-His tag
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产品编号
KMH1161
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别名
神经生长因子受体α2，NTNRA, RETL2, TRNR2, GDNFRB, NRTNR ALPHA, GDNF family receptor alpha 2
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Catalog Number | KMH1161 |
| Alias | 神经生长因子受体α2，NTNRA, RETL2, TRNR2, GDNFRB, NRTNR ALPHA, GDNF family receptor alpha 2 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH1161 Recombinant Human GFRA2 C-fc Protein, C-His tag contains the human GFRA2(Ser22-Ser441) was in Mammalian cells. |
| Molecular Name | GFRA2 |
| Product Introduction | GFRA2 (KMH1161) 是神经生长因子受体家族的一员，参与神经发育与修复过程。 |
| Molecular Weight | 70-75 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | O00451 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Glial cell line-derived neurotrophic factor family receptor alpha-2, also known as GFRA2, is the cognate co-receptor for the neurotrophic factor neurturin that is selectively expressed by isolectin B(4) (IB 4)-binding nociceptive sensory neurons. GFRA2 is required for the development of the myenteric nerve plexus and is an excellent candidate gene for Hirschsprung disease (HSCR). GFRalpha2 signaling is also needed for development of the parasympathetic islet innervation that is critical for vagally induced hormone secretion. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | Other protein |
| Biological Activity | Immobilized recombinant Human Neurturin at 5 μg/mL (100 μL/well) can bind recombinant Human GFRA2, the EC50 of Human GFRA2 is 1.82 μg/mL. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
FAQ
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如何确保蛋白表达的质量？
通过优化表达条件、使用高质量的培养基和转染试剂，并通过纯化后检测蛋白的活性和纯度来确保蛋白质量。
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