Recombinant Human FGF-23 Protein, C-His tag
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产品编号
KMH1094
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别名
成纤维生长因子23, ADHR, FGFN, HYPF, HFTC2, HPDR2, PHPTC, fibroblast growth factor 23
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Catalog Number | KMH1094 |
| Alias | 成纤维生长因子23, ADHR, FGFN, HYPF, HFTC2, HPDR2, PHPTC, fibroblast growth factor 23 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | KMH1094 Recombinant Human FGF-23 Protein, C-His tag contains the human FGF23(25-251 aa) was expressed in Mammalian cells. |
| Molecular Name | FGF23 |
| Product Introduction | FGF23 (KMH1094) 调节矿物质代谢，参与肾脏对磷酸盐和钙的重吸收。 |
| Molecular Weight | 30-35 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| Purification | Affinity Purification |
| Uniprot ID | Q9GZV9 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | FGF-23 is a member of the fibroblast growth factor (FGF) family. FGF-23 inhibits renal tubular phosphate transport. This gene was identified by its mutations associated with autosomal dominant hypophosphatemic rickets (ADHR), an inherited phosphate wasting disorder. Abnormally high level expression of FGF23 was found in oncogenic hypophosphatemic osteomalacia (OHO), a phenotypically similar disease caused by abnormal phosphate metabolism. Mutations FGF23 have also been shown to cause familial tumoral calcinosis with hyperphosphatemia. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | Other protein |
| Biological Activity | Measured in a cell proliferation assay using BaF3 mouse pro‑B cells transfected with human FGF RIIIc. The ED50 forthis effect is 0.1‑0.4 µg/mL in the presence of Recombinant Mouse Klotho and heparin. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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