Human IGF2BP2 Protein, His Tag, GST Tag
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产品编号
KMP2858
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别名
胰岛素样生长因子结合蛋白 2, Human IGF2BP2 Protein, His Tag, GST Tag, IGF2BP2
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规格
- 50ug
- 100ug
- 200ug
Alias | 胰岛素样生长因子结合蛋白 2, Human IGF2BP2 Protein, His Tag, GST Tag, IGF2BP2 |
Catalog Number | KMP2858 |
Product Description | The Human IGF2BP2 Protein(KMP2858) is produced in Insect Cells. The target gene encoding the human IGF2BP2 isoform 1 (Q9Y6M1-2) (Met 1-Lys 599) is fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus. |
Molecular Name | IGF2BP2 |
Species | Human |
Host | Insect Cells |
Size | 50ug, 100ug, 200ug |
Purity | >75% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | 50mM Tris, 500mM NaCl, 0.5mM PMSF, 5mM Reduced Glutathione, pH8.0 |
Background | Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is a member of the IGF-II mRNA-binding protein (IMP) family. IGF2BP2 is a member of a family of mRNA binding proteins that, collectively, have been shown to bind to several different mRNAs in mammalian cells, including one of the mRNAs encoding insulin-like growth factor-2. Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is involved in the stimulation of insulin action. IGF2BP2 / IMP2 is expressed in oocytes, granulosa cells of small and growing follicles, Leydig cells, spermatogonia, and semen (at protein level). It is also expressed in testicular cancer (at protein level). It is expressed weakly in the heart, placenta, skeletal muscle, bone marrow, colon, kidney, salivary glands, testis, and pancreas. IGF2BP2 binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. This binding is isoform-specific. IGF2BP2 may regulate the translation of target mRNAs. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 94 kDa |