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Human IGF2BP2 Protein, His Tag, GST Tag

Human IGF2BP2 Protein, His Tag, GST Tag

产品编号

KMP2858

别名

胰岛素样生长因子结合蛋白 2, Human IGF2BP2 Protein, His Tag, GST Tag, IGF2BP2

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias胰岛素样生长因子结合蛋白 2, Human IGF2BP2 Protein, His Tag, GST Tag, IGF2BP2
Catalog NumberKMP2858
Product DescriptionThe Human IGF2BP2 Protein(KMP2858) is produced in Insect Cells. The target gene encoding the human IGF2BP2 isoform 1 (Q9Y6M1-2) (Met 1-Lys 599) is fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
Molecular NameIGF2BP2
SpeciesHuman
HostInsect Cells
Size50ug, 100ug, 200ug
Purity>75% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation50mM Tris, 500mM NaCl, 0.5mM PMSF, 5mM Reduced Glutathione, pH8.0
BackgroundInsulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is a member of the IGF-II mRNA-binding protein (IMP) family. IGF2BP2 is a member of a family of mRNA binding proteins that, collectively, have been shown to bind to several different mRNAs in mammalian cells, including one of the mRNAs encoding insulin-like growth factor-2. Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is involved in the stimulation of insulin action. IGF2BP2 / IMP2 is expressed in oocytes, granulosa cells of small and growing follicles, Leydig cells, spermatogonia, and semen (at protein level). It is also expressed in testicular cancer (at protein level). It is expressed weakly in the heart, placenta, skeletal muscle, bone marrow, colon, kidney, salivary glands, testis, and pancreas. IGF2BP2 binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. This binding is isoform-specific. IGF2BP2 may regulate the translation of target mRNAs.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight94 kDa

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