Human LIMPII Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human LIMPII Protein, hFc Tag

Human LIMPII Protein, hFc Tag

产品编号

KMP2843

别名

溶酶体整合膜蛋白, Human LIMPII Protein, hFc Tag, LIMPII

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	溶酶体整合膜蛋白, Human LIMPII Protein, hFc Tag, LIMPII
Catalog Number	KMP2843
Product Description	The Human LIMPII Protein(KMP2843) is produced in HEK293 Cells. The target gene encoding the human SIGLEC15 (NP_005497.1) (Arg27-Thr432) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name	LIMPII
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Lysosomal Integral Membrane Protein II (LIMPII), also known as SCARB2, LPG85, and CD36L2, is a type I II multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. This protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. LIMPII is identified as a receptor for EV71 (human enterovirus species A, Enterovirus 71) and CVA16 (coxsackievirus A16) which are most frequently associated with hand, foot and mouth disease (HFMD). Expression of human LIMPII enables normally unsusceptible cell lines to support the viruses’ propagation and develop cytopathic effects. In addition, LIMPII also has been shown to bind thrombospondin-1, and may contribute to the pro-adhesive changes of activated platelets during coagulation, and inflammation. Deficiency of the protein in mice impairs cell membrane transport processes and causes pelvic junction obstruction, deafness, and peripheral neuropathy.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	73.26 kDa

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