Human NGF Protein
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产品编号
KMP2841
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别名
神经生长因子, Human NGF Protein, NGF
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规格
- 50ug
- 100ug
- 200ug
Alias | 神经生长因子, Human NGF Protein, NGF |
Catalog Number | KMP2841 |
Product Description | The Human NGF Protein(KMP2841) is produced in E. coli. The target gene encoding the human NGF (NP_002497.2) (Glu19-Ala241) is expressed with an initial Met. |
Molecular Name | NGF |
Species | Human |
Host | E. coli |
Size | 50ug, 100ug, 200ug |
Purity | >85% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | 0.01% TFA, 40% Acetonitrile |
Background | Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF (beta-NGF), was demonstrated to exhibits the growth-stimulating activity of NGF protein. NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein that homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. Also, previous studies indicated that NGF may also have an important role in the regulation of the immune system. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 25.1 kDa |