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Human NGF Protein

Human NGF Protein

产品编号

KMP2841

别名

神经生长因子, Human NGF Protein, NGF

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias神经生长因子, Human NGF Protein, NGF
Catalog NumberKMP2841
Product DescriptionThe Human NGF Protein(KMP2841) is produced in E. coli. The target gene encoding the human NGF (NP_002497.2) (Glu19-Ala241) is expressed with an initial Met.
Molecular NameNGF
SpeciesHuman
HostE. coli
Size50ug, 100ug, 200ug
Purity>85% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation0.01% TFA, 40% Acetonitrile
BackgroundNerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF (beta-NGF), was demonstrated to exhibits the growth-stimulating activity of NGF protein. NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein that homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. Also, previous studies indicated that NGF may also have an important role in the regulation of the immune system.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight25.1 kDa

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