Human CD8 beta Protein_天津卡梅德科技发展有限公司

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Human CD8 beta Protein

Human CD8 beta Protein

产品编号

KMP2834

别名

白细胞分化抗原, Human CD8 beta Protein, CD8 beta

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	白细胞分化抗原, Human CD8 beta Protein, CD8 beta
Catalog Number	KMP2834
Product Description	The Human CD8 beta Protein(KMP2834) is produced in HEK293 Cells. The target gene encoding the extracellular domain of human CD8B (P10966-1) (Met1-Pro170) is expressed with six amino acids (LEVLFQ) at the C- terminus. The purified protein is biotinylated in vitro.
Molecular Name	CD8 beta
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>85% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS
Background	CD8B (CD8b molecule), also known as P37 and LEU2, contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. P37 gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. CD8 is thought to play a role in the process of T-cell mediated killing.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	17.6 kDa

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