Human TFRC Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human TFRC Protein, hFc Tag

Human TFRC Protein, hFc Tag

产品编号

KMP2825

别名

转铁蛋白受体1, Human TFRC Protein, hFc Tag, TFRC

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	转铁蛋白受体1, Human TFRC Protein, hFc Tag, TFRC
Catalog Number	KMP2825
Product Description	The Human TFRC Protein(KMP2825) is produced in HEK293 Cells. The target gene encoding the human TFRC (CAA25527.1) (Cys89-Phe760) is expressed with the Fc region of human IgG1 at the N-terminus.
Molecular Name	TFRC
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>85% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	103.6 kDa

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