Biotinylated Human CD8 Alpha Protein, His & Avi Tag_天津卡梅德科技发展有限公司

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Biotinylated Human CD8 Alpha Protein, His & Avi Tag

Biotinylated Human CD8 Alpha Protein, His & Avi Tag

产品编号

KMP2815

别名

分化群8, Human CD8 alpha Protein, His Tag, CD8 alpha

规格

50ug
100ug
200ug

DATASHEET COA

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产品介绍

Alias	分化群8, Human CD8 alpha Protein, His Tag, CD8 alpha
Catalog Number	KMP2815
Product Description	The Biotinylated Human CD8 Alpha Protein(KMP2815) is produced in CHO Cells. The target gene encoding the extracellular domain of human CD8A (NP_001759.3) (Met1-Asp182) is expressed with a C-terminal polyhistidine tag. The purified protein is biotinylated in vitro.
Molecular Name	CD8 alpha
Species	Human
Host	CHO Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been implicated in the recognition of monomorphic determinants on major histocompatibility complex (MHC) Class I antigens, and in signal transduction during the course of T-cell activation. Both human and rodent CD8 antigens are comprised of two distinct polypeptide chains, alpha and beta. The Ig domains of CD8 alpha are involved in controlling the ability of CD8 to be expressed. Mutation of B- and F-strand cysteine residues in CD8 alpha reduced the ability of the protein to fold properly and, therefore, to be expressed. Defects in CD8A are a cause of familial CD8 deficiency. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.
Storage Condition	分装并储存于-20℃至-80℃。避免反复冻融循环。
Shipping Condition	一般来说，重组蛋白以冻干粉的形式提供，并在室温下运输。如果以液体形式提供，则蛋白质将与干冰一起运输。
Molecular Weight	19 kDa
Product Declaration	产品仅用于科研使用

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