Human Renin Protein, His Tag_天津卡梅德科技发展有限公司

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Human Renin Protein, His Tag

Human Renin Protein, His Tag

产品编号

KMP2807

别名

肾素, Human Renin Protein, His Tag, Renin

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	肾素, Human Renin Protein, His Tag, Renin
Catalog Number	KMP2807
Product Description	The Human Renin Protein(KMP2807) is produced in HEK293 Cells. The target gene encoding the human REN (NP_000528.1, with mutation Arg 66 Lys) (Met1-Arg406) is expressed with a polyHistide tag at the C-terminus.
Molecular Name	Renin
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	50mM Tris, 150mM NaCl, pH8.0
Background	Renin-1, also known as Ren-1, Angiotensinogenase and Kidney renin, is a member of the peptidase A1 family. Renin-1 is synthesized by the juxtaglomerular cells of the kidney in response to decreased blood pressure and sodium concentration. androgen and thyroid hormones influence levels of Renin-1 in mouse submandibular gland (SMG) primarily by regulating the amount of Renin-1 mRNA available for translation. Renin-1 is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. It is expressed at relatively low levels in mouse SMG and kidney. Ren-2 is expressed at high levels in the mouse SMG and at very low levels, if at all, in the kidney. Ren-1 and Ren-2 are closely linked on mouse chromosome 1, show extensive homology in coding and noncoding regions and provide a model for studying the regulation of gene expression.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	43.74 kDa

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