Human IL13RA1 Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human IL13RA1 Protein, hFc Tag

Human IL13RA1 Protein, hFc Tag

产品编号

KMP2799

别名

白细胞介素 13 受体亚基 α 1, Human IL13RA1 Protein, hFc Tag, IL13RA1

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	白细胞介素 13 受体亚基 α 1, Human IL13RA1 Protein, hFc Tag, IL13RA1
Catalog Number	KMP2799
Product Description	The Human IL13RA1 Protein(KMP2799) is produced in HEK293 Cells. The target gene encoding the human IL13RA1 (NP_001551.1) (Met1-Thr343) is expressed with the fused Fc region of human IgG1 at the C-terminus.
Molecular Name	IL13RA1
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. IL13RA1/IL-13RA1 serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2 and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3, and STAT6 induced by IL13 and IL4. IL13RA1/IL-13RA1 binds with low affinity to interleukin-13 (IL13). This subunit together with IL4RA can form a functional receptor for IL13. IL13RA1/IL-13RA1 also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	63.62 kDa

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