Human Eotaxin-2 Protein, His Tag_天津卡梅德科技发展有限公司

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Human Eotaxin-2 Protein, His Tag

Human Eotaxin-2 Protein, His Tag

产品编号

KMP2782

别名

重组人嗜酸性粒细胞趋化因子-2, Human Eotaxin-2 Protein, His Tag, Eotaxin-2

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	重组人嗜酸性粒细胞趋化因子-2, Human Eotaxin-2 Protein, His Tag, Eotaxin-2
Catalog Number	KMP2782
Product Description	The Human Eotaxin-2 Protein(KMP2782) is produced in Insect Cells. The target gene encoding the human CCL24 (O00175) (Met 1-Cys 119) is fused with a polyhistidine tag at the C-terminus.
Molecular Name	Eotaxin-2
Species	Human
Host	Insect Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	20mM Tris, 500mM NaCl, 10% Glycerol, pH7.4
Background	CCL24, also known as Eotaxin-2 and MPIF-2, belongs to the intercrine beta (chemokine CC) family. CCL24 gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. CCL24 displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. CCL24 is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. CCL24 is chemotactic for resting T-lymphocytes, and eosinophils. It has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. It is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Eotaxin-2 interacts with chemokine receptor CCR3 to induce chemotaxis in eosinophils. Elevated level of Eotaxin-2 has been seen in patients with aspirin-exacerbated respiratory disease.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	11.8 kDa

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