Human CCL4 Protein, His Tag_天津卡梅德科技发展有限公司

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Human CCL4 Protein, His Tag

Human CCL4 Protein, His Tag

产品编号

KMP2779

别名

趋化因子 CCL4, Human CCL4 Protein, His Tag, CCL4

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	趋化因子 CCL4, Human CCL4 Protein, His Tag, CCL4
Catalog Number	KMP2779
Product Description	The Human CCL4 Protein(KMP2779) is produced in Yeast. The target gene encoding human CCL4 (NP_002975.1) (Ala24-Gln92) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	CCL4
Species	Human
Host	Yeast
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	0.1% TFA
Background	CCL4 (C-C chemokine ligand 4), is a macrophage inflammatory protein with a chief effect in inflammation and immune-regulation, and was documented in cancer progression by promoting instability in the tumor environment. The inflammatory chemokine (C-C motif) ligand 4 (CCL4) plays an important role in the pathogenesis and progression of cancer. In particular, higher serum CCL4 levels in patients with oral squamous cell carcinoma (OSCC) are associated with a more advanced stage of disease. CCL4 may be a new molecular therapeutic target for inhibition of lymphangiogenesis and metastasis in OSCC. CCL3 and CCL4 loci may be marker SNPs for risk of HCV treatment outcome. CCL4 can enhance the recruitment of preosteoclasts to bone in the early stage, and the reduction of CCR5 promotes osteoclastogenesis when RANKL is prevalent.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	9.2 kDa

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