Human MIP-5 Protein, His Tag_天津卡梅德科技发展有限公司

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Human MIP-5 Protein, His Tag

Human MIP-5 Protein, His Tag

产品编号

KMP2777

别名

巨噬细胞炎症蛋白, Human MIP-5 Protein, His Tag, MIP-5

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	巨噬细胞炎症蛋白, Human MIP-5 Protein, His Tag, MIP-5
Catalog Number	KMP2777
Product Description	The Human MIP-5 Protein(KMP2777) is produced in E. coli. The target gene encoding the mature form of human CCL15 (Q16663-1) (Gln 22-Ile 113) is expressed, with a polyHistide tag at the C-terminus.
Molecular Name	MIP-5
Species	Human
Host	E. coli
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokine ligand 15 (CCL15), also known as leukotactin-1, MIP5, MIP1 and HCC-2, is a small cytokine belonging to the C-C chemokine family. CCL15 is prevantly expressed in liver, small intestine, colon, and in certain leukocytes and macrophages of the lung. It is chemotactic for neutrophils, monocytes, and lymphocytes and elicits its effects by binding to cell surface chemokine receptors like CCR1 and CCR3.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	11.7 kDa

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