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Human Ephrin-A1 Protein, hFc Tag

Human Ephrin-A1 Protein, hFc Tag

产品编号

KMP2766

别名

肾上腺素 A1, Human Ephrin-A1 Protein, hFc Tag, Ephrin-A1

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias肾上腺素 A1, Human Ephrin-A1 Protein, hFc Tag, Ephrin-A1
Catalog NumberKMP2766
Product DescriptionThe Human Ephrin-A1 Protein(KMP2766) is produced in HEK293 Cells. The target gene encoding the human EFNA1 (NP_004419.2) (Met1-Ser182) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular NameEphrin-A1
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundEPH-related receptor tyrosine kinase ligand 1 (abbreviated as Ephrin-A1) also known as ligand of eph-related kinase 1 or EFNA1, is a member of the ephrin (EPH) family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Ephrin-A1/EFNA1 and its Eph family of receptor tyrosine kinases are expressed by cells of the SVZ. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. An exception is the EphA4 receptor, which binds both subclasses of ephrins. Ephrin-A1 and one of its receptor EphA2 were expressed in xenograft endothelial cells and also tumor cells and play a role in human cancers, at least in part by influencing tumor neovascularization.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight46.08 kDa

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