Human CXCL14 Protein
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产品编号
KMP2765
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别名
CXC 基序趋化因子配体, Human CXCL14 Protein, CXCL14
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规格
- 50ug
- 100ug
- 200ug
Alias | CXC 基序趋化因子配体, Human CXCL14 Protein, CXCL14 |
Catalog Number | KMP2765 |
Product Description | The Human CXCL14 Protein(KMP2765) is produced in E. coli. The target gene encoding human CXCL14 (O95715) (Ser35-Glu111) is expressed with a N-terminal Met. The purified protein is biotinylated in vitro. |
Molecular Name | CXCL14 |
Species | Human |
Host | E. coli |
Size | 50ug, 100ug, 200ug |
Purity | >90% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | CXCL14 is a CXC chemokine family that exhibits antimicrobial activity and contains an amphipathic cationic alpha-helical region in the C-terminus, a characteristic structure of antimicrobial peptides (AMPs). CXCL14 is involved in cell recruitment, migration, activation, and homing in liver diseases and have been shown to be upregulated during acute liver injury in animal models. The CXC chemokine ligand 14 (CXCL14) had been show highly expressed in tumor-associated stromal cells, promoting tumor cell growth, and invasion. The stimulation of dysregulated CXCL14 expression by P. gingivalis may help promote dysbiosis and the development of chronic periodontitis. The level of CXCL14 expression may be a valuable adjuvant parameter to predict the prognosis of patients with oral carcinoma and may be a potential therapeutic target. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 9.4 kDa |