Human CXCL17 Protein, His Tag_天津卡梅德科技发展有限公司

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Human CXCL17 Protein, His Tag

Human CXCL17 Protein, His Tag

产品编号

KMP2762

别名

CXC趋化因子配体 17, Human CXCL17 Protein, His Tag, CXCL17

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	CXC趋化因子配体 17, Human CXCL17 Protein, His Tag, CXCL17
Catalog Number	KMP2762
Product Description	The Human CXCL17 Protein(KMP2762) is produced in Yeast. The target gene encoding the human CXCL17 (NP_940879.1) (Leu24-Leu119) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	CXCL17
Species	Human
Host	Yeast
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Chemokine (C-X-C motif) ligand 17 (CXCL17) is the latest member of the chemokine family. CXCL17 is a potential oncogene and promising therapeutic target, is an independent biomarker of poor prognosis in patients with breast cancer, and can promote proliferation and migration of breast cancer cells in vitro and in vivo. CXCL17 is expressed in a variety of cancers and promotes tumor progression by recruiting myeloid-derived suppressor cells (MDSCs). CXCL17 attenuates IMQ-induced psoriasis-like skin inflammation by recruiting MDSCs and Tregs, which may be important for regulating excessive inflammation in psoriasis skin. CXCL17 production correlated with adverse immune infiltration and might be an important target for anti-HCC therapies. CXCL17 is a major regulator of mucosal inflammatory responses.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	12.7 kDa

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