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Human CD120a Protein, hFc Tag

Human CD120a Protein, hFc Tag

产品编号

KMP2756

别名

肿瘤坏死因子受体超家族成员 1A, Human CD120a Protein, hFc Tag, CD120a

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias肿瘤坏死因子受体超家族成员 1A, Human CD120a Protein, hFc Tag, CD120a
Catalog NumberKMP2756
Product DescriptionThe Human CD120a Protein(KMP2756) is produced in HEK293 Cells. The target gene encoding the human TNFRSF1A (NP_001056.1) (Met1-Thr211) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular NameCD120a
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundThe cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behAvior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD120a (cluste of differentiation 120a), also known as TNFR1 / TNFRSF1A, is a member of CD family, tumor necrosis factor receptor superfamily. CD120a is one of the most primary receptors for the tumor necrosis factor-alpha. It has been shown to be localized to both plasma membrane lipid rafts and the trans golgi complex with the help of the death domain (DD). CD120a can activate the transcription factor NF-κB, mediate apoptosis, and regulate inflammation processes.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight48 kDa

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