Human CEACAM6 Protein, His Tag, Avi Tag_天津卡梅德科技发展有限公司

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Human CEACAM6 Protein, His Tag, Avi Tag

Human CEACAM6 Protein, His Tag, Avi Tag

产品编号

KMP2753

别名

CEA 细胞粘附分子, Human CEACAM6 Protein, His Tag, Avi Tag, CEACAM6

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	CEA 细胞粘附分子, Human CEACAM6 Protein, His Tag, Avi Tag, CEACAM6
Catalog Number	KMP2753
Product Description	The Human CEACAM6 Protein(KMP2753) is produced in HEK293 Cells. The target gene encoding the Human CEACAM6 (NP_002474.3) (Met1-Gly320) is expressed with a C-terminal polyhistidine tag followed by an Avi tag. The expressed protein is biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
Molecular Name	CEACAM6
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), also known as nonspecific crossreacting antigen (NCA) and CD66c, is one of seven human CEACAM family members within the immunoglobulin superfamily. It s a glycosylphosphatidylinositol-linked immunoglobulin superfamily member that is overexpressed in a variety of human cancers, including colon, breast and lung and is associated with tumourigenesis, tumour cell adhesion, invasion and metastasis. CEACAM6 is a unique mediator of migration and invasion of drug resistant oestrogen-deprived breast cancer cells, and this protein could be an important biomarker of metastasis. CEACAM6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	34.47 kDa

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