Human CEACAM1 Protein, His Tag, hFc Tag_天津卡梅德科技发展有限公司

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Human CEACAM1 Protein, His Tag, hFc Tag

Human CEACAM1 Protein, His Tag, hFc Tag

产品编号

KMP2750

别名

癌胚抗原相关细胞粘附分子1, Human CEACAM1 Protein, His Tag, hFc Tag, CEACAM1

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	癌胚抗原相关细胞粘附分子1, Human CEACAM1 Protein, His Tag, hFc Tag, CEACAM1
Catalog Number	KMP2750
Product Description	The Human CEACAM1 Protein(KMP2750) is produced in HEK293 Cells. The target gene encoding the extracellular domain of human CEACAM1 (NP_001020083.1) (Met 1-Gly 428) is fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
Molecular Name	CEACAM1
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	100mM Glycerolcine, 500mM NaCl, 5% Glycerol, 50mM Arg HCl, 50mM Glu, 0.01% Tween 20, pH5.0
Background	The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and differentiation of normal and cancerous cells. CEACAM1, also known as biliary glycoprotein I (BGP I) and CD66a, is a member of the carcinoembryonic antigen (CEA) gene family which belongs to the immunoglobulin superfamily. The highly glycosylated CEACAM1 contains one N-terminal V-type Ig-like domain and three C2-type Ig-like domains within its ECD, and one ITIM motif and a calmodulin binding site in the cytoplasmic region. CEACAM1 is a surface glycoprotein expressed on various blood cells, epithelial cells, and vascular cells. It was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	71.4 kDa

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