Human FLT4 Protein, His Tag, Avi Tag_天津卡梅德科技发展有限公司

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Human FLT4 Protein, His Tag, Avi Tag

Human FLT4 Protein, His Tag, Avi Tag

产品编号

KMP2744

别名

血管内皮生长因子受体3, Human FLT4 Protein, His Tag, Avi Tag, FLT4

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	血管内皮生长因子受体3, Human FLT4 Protein, His Tag, Avi Tag, FLT4
Catalog Number	KMP2744
Product Description	The Human FLT4 Protein(KMP2744) is produced in HEK293 Cells. The target gene encoding the human VEGFR3/FLT4 (NP_002011.2) (Met1-Ile776) is expressed with a C-terminal Avi tag followed by a His tag. The expressed protein is biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
Molecular Name	FLT4
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). The VEGFR3 protein is expressed mainly on lymphatic vessels but it is also up-regulated in tumor angiogenesis. Mutations in VEGFR3 have been identified in patients with primary lymphoedema. The VEGF-C/VEGF-D/VEGFR3 signaling pathway may provide a target for antilymphangiogenic therapy in prostate cancer, breast cancer, gastric cancer, lung cancer, non-small cell lung cancer (NSCLC), and so on.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	87.80 kDa

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