Human CD30 Protein, His Tag, Avi Tag_天津卡梅德科技发展有限公司

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Human CD30 Protein, His Tag, Avi Tag

Human CD30 Protein, His Tag, Avi Tag

产品编号

KMP2732

别名

白细胞抗原分化簇30, Human CD30 Protein, His Tag, Avi Tag, CD30

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	白细胞抗原分化簇30, Human CD30 Protein, His Tag, Avi Tag, CD30
Catalog Number	KMP2732
Product Description	The Human CD30 Protein(KMP2732) is produced in HEK293 Cells. The target gene encoding the human TNFRSF8 (NP_001234.2) (Met1-Lys379) is expressed with a C-terminal polyhistidine tag followed by an Avi tag. The expressed protein is biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
Molecular Name	CD30
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of lymphocytes and may also play an important role in human immunodeficiency virus replication. As a regulator of apoptosis, CD30 protein induces cell death or proliferation, depending on the cell type, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. CD30 protein expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs), and CD30 is also linked to leukocytes in patients with chronic inflammatory diseases, including lupus erythematosus, asthma, rheumatoid arthritis and atopic dermatitis (AD).
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	41.74 kDa

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