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Human CD30 Protein, His Tag

Human CD30 Protein, His Tag

产品编号

KMP2731

别名

白细胞抗原分化簇30, Human CD30 Protein, His Tag, CD30

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias白细胞抗原分化簇30, Human CD30 Protein, His Tag, CD30
Catalog NumberKMP2731
Product DescriptionThe Human CD30 Protein(KMP2731) is produced in HEK293 Cells. The target gene encoding the TNFRSF8 (NP_001234.2) (Met1-Lys379) is expressed with a C-terminal polyhistidine tag. The purified protein is biotinylated in vitro.
Molecular NameCD30
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS
BackgroundCD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of lymphocytes and may also play an important role in human immunodeficiency virus replication. As a regulator of apoptosis, CD30 protein induces cell death or proliferation, depending on the cell type, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. CD30 protein expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs), and CD30 is also linked to leukocytes in patients with chronic inflammatory diseases, including lupus erythematosus, asthma, rheumatoid arthritis and atopic dermatitis (AD).
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight39.9 kDa

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