Human CXCL10 Protein_天津卡梅德科技发展有限公司

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Human CXCL10 Protein

Human CXCL10 Protein

产品编号

KMP2721

别名

C-X-C基序趋化因子配体10, Human CXCL10 Protein, CXCL10

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	C-X-C基序趋化因子配体10, Human CXCL10 Protein, CXCL10
Catalog Number	KMP2721
Product Description	The Human CXCL10 Protein(KMP2721) is produced in E. coli. The target gene encoding the mature form of human CXCL10 (NP_001556.2) (Val22-Pro98) is expressed, with a N-terminal Met.
Molecular Name	CXCL10
Species	Human
Host	E. coli
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS
Background	(C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor coupled to G proteins. CXCL10/IP-10 and its receptor, CXCR3, appear to contribute to the pathogenesis of many autoimmune diseases, organ specific (such as type 1 diabetes, autoimmune thyroiditis, Graves' disease and ophthalmopathy), or systemic (such as rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus, mixed cryoglobulinemia, Sjögren syndrome, or systemic sclerosis). CXCL10/IP-10 is secreted by several cell types including endothelial cells, fibroblasts, keratinocytes, thyrocytes, preadipocytes, etc. Determination of high level of CXCL10/IP-10 in peripheral fluids is therefore a marker of host immune response.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	8.8 kDa

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