Human TIE2 Protein, His Tag_天津卡梅德科技发展有限公司

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Human TIE2 Protein, His Tag

Human TIE2 Protein, His Tag

产品编号

KMP2711

别名

内皮细胞TEK酪氨酸激酶, Human TIE2 Protein, His Tag, TIE2

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	内皮细胞TEK酪氨酸激酶, Human TIE2 Protein, His Tag, TIE2
Catalog Number	KMP2711
Product Description	The Human TIE2 Protein(KMP2711) is produced in HEK293 Cells. The target gene encoding the extracellular domain (Met1-Lys745) of human Tie2 (AAA61139.1) precursor is fused with a polyhistidine tag at the C-terminus. The purified protein is biotinylated in vitro.
Molecular Name	TIE2
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	TEK, or TIE-2, is an endothelial cell-specific receptor tyrosine kinase (RTK) that is known as a functioning molecule of vascular endothelial cells. TEK comprises a subfamily of RTK with TIE, and these two receptors play critical roles in vascular maturation, maintenance of integrity and remodeling. Targeted mutagenesis of both Tek and its agonistic ligand, Angiopoietin-1, result in embryonic lethality, demonstrating that the signal transduction pathways mediated by this receptor are crucial for normal embryonic development. TEK signaling is indispensable for the development of the embryonic vasculature and suggests that TEK signaling may also be required for the development of the tumor vasculature.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	82 kDa

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