Human CD86 Protein, His Tag_天津卡梅德科技发展有限公司

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Human CD86 Protein, His Tag

Human CD86 Protein, His Tag

产品编号

KMP2709

别名

重组白细胞分化抗原86, Human CD86 Protein, His Tag, CD86

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	重组白细胞分化抗原86, Human CD86 Protein, His Tag, CD86
Catalog Number	KMP2709
Product Description	The Human CD86 Protein(KMP2709) is produced in HEK293 Cells. The target gene encoding the extracellular domain (Met1-His239) of human B7-2 (NP_008820.2) is fused with a polyhistidine tag at the C-terminus. The purified protein is biotinylated in vitro.
Molecular Name	CD86
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS
Background	CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B and T helper cells mediated by CD86 encourage signals for the proliferation and IgG secretion of normal B cells and B cell lymphomas. A recent study has revealed that CD86 also promotes the generation of a mature APC repertoire and promotes APC function and survival. CD86 has an important role in chronic hemodialysis, allergic pulmonary inflammation, arthritis, and antiviral responses, and thus is regarded as a promising candidate for immune therapy.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	26.2 kDa

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