Human B7-1 Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human B7-1 Protein, hFc Tag

Human B7-1 Protein, hFc Tag

产品编号

KMP2706

别名

抗原分化簇80, Human B7-1 Protein, hFc Tag, B7-1

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	抗原分化簇80, Human B7-1 Protein, hFc Tag, B7-1
Catalog Number	KMP2706
Product Description	The Human B7-1 Protein(KMP2706) is produced in HEK293 Cells. The target gene encoding the human CD80 (NP_005182.1) (Met1-Asn242) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name	B7-1
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. As costimulatory ligands, B7-1 which exists predominantly as dimer and the related protein B7-2, interact with the costimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus constitute one of the dominant pathways that regulate T cell activation and tolerance, cytokine production, and the generation of CTL. The B7/CD28/CTLA4 pathway has the ability to both positively and negatively regulate immune responses. CD80 is thus regarded as promising therapeutic targets for autoimmune diseases and various carcinomas.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	50.6 kDa

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