Human CD122 Protein, mFc Tag_天津卡梅德科技发展有限公司

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Human CD122 Protein, mFc Tag

Human CD122 Protein, mFc Tag

产品编号

KMP2703

别名

白介素-2 受体 beta, Human CD122 Protein, mFc Tag, CD122

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	白介素-2 受体 beta, Human CD122 Protein, mFc Tag, CD122
Catalog Number	KMP2703
Product Description	The Human CD122 Protein(KMP2703) is produced in HEK293 Cells. The target gene encoding the human IL2RB (NP_000869.1) (Met1-Asp239) is expressed with the Fc region of mouse IgG1 at the C-terminus.
Molecular Name	CD122
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Interleukin-2 receptor (IL-2R) also known as High-affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, and IL-2RB, is involved in T cell-mediated immune responses. CD122/IL-2RB is present in 3 forms concerning the ability to bind interleukin 2. The low-affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high-affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high-affinity forms of CD122/IL-2RB are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. CD122/IL-2RB expression was restricted to the earliest B220+ cells (CD43+CD24-; prepro B cells; fraction A) that proliferate vigorously to IL-2 in the absence of any stromal cells, but not to IL-15. The high-affinity form of this receptor is expressed on activated T lymphocytes, activated B lymphocytes, and activated macrophages. CD122/IL-2RB plays a role in regulating normal lymphocyte development.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	51 kDa

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