Human EpCAM Protein, hFc Tag_天津卡梅德科技发展有限公司

>>

>>

>>

>

Human EpCAM Protein, hFc Tag

Human EpCAM Protein, hFc Tag

产品编号

KMP2698

别名

上皮细胞粘附分子, Human EpCAM Protein, hFc Tag, EpCAM

规格

50ug
100ug
200ug

DATASHEET MSDS

立即询价加入询价列表大包装定制

产品介绍

Alias	上皮细胞粘附分子, Human EpCAM Protein, hFc Tag, EpCAM
Catalog Number	KMP2698
Product Description	The Human EpCAM Protein(KMP2698) is produced in HEK293 Cells. The target gene encoding the EPCAM (NP_002345.1) (Met1-Lys265) is expressed with the fused Fc region of human IgG1 at the C-terminus. The purified protein is biotinylated in vitro.
Molecular Name	EpCAM
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS
Background	Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane domain and a cytoplasmic domain. It modulates cell adhesion and proliferation. Its overexpression has been detected in many epithelial tumours and has been associated with high stage, high grade and a worse survival in some tumour types. EpCAM has been shown to function as a calcium-independent homophilic cell adhesion molecule that does not exhibit any obvious relationship to the four known cell adhesion molecule superfamilies. However, recent insights have revealed that EpCAM participates in not only cell adhesion, but also in proliferation, migration and differentiation of cells. In addition, recent study revealed that EpCAM is the Wnt-beta-catenin signaling target gene and may be used to facilitate prognosis. It has oncogenic potential and is activated by release of its intracellular domain, which can signal into the cell nucleus by engagement of elements of the wnt pathway.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	54.1 kDa

推荐产品

400-621-6806
614353794
周一至周五 9:00-18:00
0