Human c-MET Protein, His Tag, Avi Tag_天津卡梅德科技发展有限公司

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Human c-MET Protein, His Tag, Avi Tag

Human c-MET Protein, His Tag, Avi Tag

产品编号

KMP2697

别名

间质表皮转化因子, Human c-MET Protein, His Tag, Avi Tag, c-MET

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	间质表皮转化因子, Human c-MET Protein, His Tag, Avi Tag, c-MET
Catalog Number	KMP2697
Product Description	The Human c-MET Protein(KMP2697) is produced in HEK293 Cells. The target gene encoding the human MET (NP_000236.2) (Met1-Thr932) is expressed with a c-terminal polyhistidine tagged Avi tag at the C-terminus. The expressed protein is biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
Molecular Name	c-MET
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR protein is produced as a single-chain precursor, and HGF is the only known ligand. Normal HGF/HGFR signaling is essential for embryonic development, tissue repair, or wound healing, whereas aberrantly active HGFR has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes. HGFR protein is a multifaceted regulator of growth, motility, and invasion, and is normally expressed by cells of epithelial origin. Preclinical studies suggest that targeting aberrant HGFR signaling could be an attractive therapy in cancer.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	104.9 kDa

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