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Human TNF-alpha Protein, hFc Tag

Human TNF-alpha Protein, hFc Tag

产品编号

KMP2663

别名

肿瘤坏死因子α, Human TNF-alpha Protein, hFc Tag, TNF-alpha

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias肿瘤坏死因子α, Human TNF-alpha Protein, hFc Tag, TNF-alpha
Catalog NumberKMP2663
Product DescriptionThe Human TNF-alpha Protein(KMP2663) is produced in HEK293 Cells. The target gene encoding the human TNF (NP_000585.2) (Val77-Leu233) is expressed with the Fc region of human IgG1 at the N-terminus.
Molecular NameTNF-alpha
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundTumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.TNF-alpha Protein & Antibody
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight45.8 kDa

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