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Human Integrin beta 1 Protein, His Tag

Human Integrin beta 1 Protein, His Tag

产品编号

KMP2659

别名

整合素亚基 β 1 结合蛋白 1, Human Integrin beta 1 Protein, His Tag, Integrin beta 1

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias整合素亚基 β 1 结合蛋白 1, Human Integrin beta 1 Protein, His Tag, Integrin beta 1
Catalog NumberKMP2659
Product DescriptionThe Human Integrin beta 1 Protein(KMP2659) is produced in HEK293 Cells. The target gene encoding the human ITGB1 (CAA30790.1) (Met1-Asp728) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameIntegrin beta 1
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involved in cell functions such as proliferation, migration, invasion, and survival. ITGB1 has been recognized to play a major role in tumor growth, invasion, and metastasis. Using luciferase assays, the researcher identified ITGB1 as a direct target of miR-134. ITGB1 is a direct target of miR-493-5p suggesting that ITGB1 and miR-493-5p may have potential prognostic value and may be useful as tumor biomarkers for the diagnosis of NSCLC patients. Diseases associated with ITGB1 include Gallbladder Cancer and Breast Cancer.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight83.3 kDa

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